Description | camptothecine camptothecin 10-hydroxy camptotheccnum 9-nitrocellulose camptotheccnum
camptothecine camptothecin 10-hydroxy camptotheccnum 9-nitrocellulose camptotheccnum
physical properties raw material nothapodytes foetida (wt) miers (icainaceae)
preparation total extractives of powdered wood suing a solvent, further processing and purification.
physical characteristics pale yellow coloured powder, mp 257-260 deg. c soluble in dmf (dimethyl formamide)
chemical characteristics common names camptothecine
chemical name (s) 4-ethyl-4-hydroxy-ih-pyrano indolizino (1,2,-b) quinoline 3,14 (4h, 12h)-dione
molecular formula c20 h16 n2 04
molecular weight 346.34
identification
ir (kbr)
uv (max)
specific optical rotation
v max 3400 1745 1655 1605 & 1580 cm
l max 220, 253 & 358 nm
+31.3 deg. (in chloroform-methanol)
purity
usp std by hplc 98% +.
toxicity highly toxic
use anti cancer activity, raw material for topotecan, cpt-11
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