functions and use: it is medicine treatment raw material, indicated for the treatment of erectile dysfunction. dissolve in water. appearance: white powder liquate:20c:15% mesylate assay:99.90% sildenafil:0.132% heavy metals: <10ppm water content:0.51% residue on ignition:0.05% mechanism: sildenafil mesylate, same as sildenafil is an inhibitor of type 5 -cgmp phosphodiesterase relaxing and smoothing muscle cells of the corpus cavernosum which leads to penile erection. this relaxation may be mediated by nitric oxide via cyclic guanosine monophosphate (cgmp). efficacy: 52% will takes effect 30 minutes after taking, 82% takes effect 1 hour after taking for sildenafil mesylate, suggested dosage should be 50-100mg, and 120mg is suggested for the orient. advantage: small dosage, small side effect, dissolve in water and ethanol.